Prof. Dr. Dr. P.Simon

Dr. E. Lachtermann

2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008


  • Hillen B, Simon P, Schlotter S, Nitsche O, Bähner V, Poplawska K, Pfirrmann D. Feasibility and implementation of a personalized, web-based exercise intervention for people with cystic fibrosis for 1 year. BMC Sports Sci Med Rehabil. 2021 Aug 19;13(1):95.
  • Reichel JL, Rigotti T, Tibubos AN, Werner AM, Schäfer M, Edelmann D, Pfirrmann D, Deci N, Beutel ME, Stark B, Simon P, Letzel S, Dietz P. Challenge Accepted! a Critical Reflection on How to Perform a Health Survey Among University Students-An Example of the Healthy Campus Mainz Project. Front Public Health. 2021 Jun 21;9:616437.
  • Neuberger EWI, Brahmer A, Ehlert T, Kluge K, Philippi KFA, Boedecker SC, Weinmann-Menke J, Simon P. Validating quantitative PCR assays for cfDNA detection without DNA extraction in exercising SLE patients.Sci Rep. 2021 Jun 30;11(1):13581
  • Hasanzadeh A, Alamdaran M, Ahmadi S, Nourizadeh H, Bagherzadeh MA, Jahromi MAM, Simon P, Karimi M, Hamblin MR.Nanotechnology against COVID-19: Immunization, diagnostic and therapeutic studies. J Control Release. 2021 Jun 24;336:354-74.
  • Neuberger EWI, Hillen B, Mayr K, Simon P, Krämer-Albers E-M, Brahmer A. Kinetics and Topology of DNA Associated with Circulating Extracellular Vesicles Released during Exercise. Genes (Basel) 2021 Apr 2; 12(4):522.


  • Considerations for the Analysis of Small Extracellular Vesicles in Physical Exercise. Brahmer A, Neuberger EWI, Simon P, Krämer-Albers EM. Front Physiol. 2020 Dec 3;11:576150.
  • Boedecker SC, Philippi KF, Neuberger E, Schmidt S, Pfirrmann D, Haller N, Schwarting A, Simon P, Weinmann-Menke J. Twelve-Week Internet-Based Individualized Exercise Program in Adults With Systemic Lupus Erythematosus: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2020 Nov 3;9(11)
  • Bahr K, Bopp M, Kewader W, Dootz H, Döge J, Huppertz T, Simon P, Prokosch-Willing V, Matthias C, Gouveris H. Obstructive sleep apnea as a risk factor for primary open angle glaucoma and ocular hypertension in a monocentric pilot study. Respir Res,2020 Oct 8;21(1):258.
  • Heller S, Ulrich R, Simon P, Dietz P. Refined Analysis of a Cross-Sectional Doping Survey Among Recreational Triathletes: Support for the Nutritional Supplement Gateway Hypothesis. Front Psychol. 2020 Sep 23;11:
  • Simon P. Robust Estimation of Infection Fatality Rates during the Early Phase of a Pandemic. MedRxiv, 2020.
  • Dietz P, Reichel JL, Edelmann D, Werner AM, Tibubos AN, Schäfer M, Simon P, Letzel S, Pfirrmann D. A Systematic Umbrella Review on the Epidemiology of Modifiable Health Influencing Factors and on Health Promoting Interventions Among University Students. Front Public Health. 2020 Apr 28;8:137.
  • Hillen B, Pfirrmann D, Nägele M, Simon P. Infrared Thermography in Exercise Physiology: The Dawning of Exercise Radiomics. Sports Med.  2020 Feb;50(2):263-282
  • Tahir E, Scherz B, Starekova J, Muellerleile K, Fischer R, Schoennagel B,Warncke M, Stehning C, Cavus E, Bohnen S, Radunski UK, Blankenberg S, Simon P,Pressler A, Adam G, Patten M, Lund GK. Acute impact of an endurance race on cardiac function and biomarkers of myocardial injury in triathletes with and without myocardial fibrosis. Eur J Prev Cardiol. 2020 Jan;27(1):94-104. Epub 2019 Jun 26.
  • “Brainstorming”: Extracellular Vesicles in Physical Activity and Neuronal Health. Brahmer A, Krämer-Albers EM. Trillium Extracellular Vesicles, 2020 Jan, Vol. 2, 11-15
  • Hoffmann SW, Dreher M, Urschitz MS, Simon P. Beyond BMI: waist circumference and social environment is associated with motor performance ability in kindergartners. BMC Pediatr. 2020 Jan 6;20(1):4.


  • Lund GK, Muellerleile K, Pressler A, Simon P, Tahir E. Reply to the letter to the editor. Eur J Prev Cardiol. 2019 Nov;26(16):1783-1784.
  • Hillen B, Simon P, Grimminger P.P, Gockel I, Pfirrmann D. Use of a Perioperative Web-Based Exercise Program for a Patient with Barrett’s Carcinoma Scheduled for Esophagectomy. Case Rep Oncol 2019;12:755–764
  • Huber Y, Pfirrmann D, Gebhardt I, Labenz C, Gehrke N, Straub BK, Ruckes C, Bantel H, Belda E, Clément K, Leeming DJ, Karsdal MA, Galle PR, Simon P, Schattenberg JM. Improvement of non-invasive markers of NAFLD from an individualised, web-based exercise program. Aliment Pharmacol Ther. 2019 Oct;50(8):930-939.
  • Ochmann D, Kreuz C, Wenzel S, Simon P. cfDNA As A Metabolic Marker. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE.Volume: 51 Issue: 6 Pages: 377-378, JUN 2019
  • Hillen B,Simon P. The Temperature Surface Radiation Pattern - A non-invasive Insight into Skin Blood Flow Response to Exercise. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, Volume: 51 Issue: 6 Pages: 491-492, JUN 2019
  • Haller N, Ehlert T, Schmidt S, Simon P. Circulating DNA As A Monitoring Tool In Professional Soccer
    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, Volume: 51 Issue: 6 Pages: 575-575, JUN 2019
  • Haller N, Ehlert T, Schmidt S, Ochmann D, Sterzing B, Grus F, Simon P. Circulating, Cell-Free DNA for Monitoring Player Load in Professional Football.Int J Sports Physiol Perform. 2019 Jul 1;14(6):718-726
  • Tahir E, Starekova J, Muellerleile K, Freiwald E, von Stritzky A, Münch J,Avanesov M, Weinrich JM, Stehning C, Cavus E, Bohnen S, Radunski UK, Blankenberg S, Adam G, Simon P, Pressler A, Patten M, Lund GK. Impact of Myocardial Fibrosis on Left Ventricular Function Evaluated by Feature-Tracking Myocardial Strain Cardiac Magnetic Resonance in Competitive Male Triathletes With Normal Ejection Fraction. Circ J. 2019 Jun 25;83(7):
  • Brahmer A, Neuberger E, Esch-Heisser L, Haller N, Jorgensen MM, Baek R, Möbius W, Simon P, Krämer-Albers EM. Platelets, endothelial cells and leukocytes contribute to the exercise-triggered release of extracellular vesicles into the circulation. J Extracell Vesicles. 2019 May 28;8(1):
  • Simon P, Dettweiler U. Current Anti-Doping Crisis: The Limits of Medical Evidence Employing Inductive Statistical Inference. Sports Med. 2019 Apr;49(4):
  • Dreher M, Hoffmann SW, Brendel C, Heser D, Simon P. Convenience Behavior and Being Overweight in Adults: Development and Validation of the Convenience Behavior Questionnaire. Front Public Health. 2019 Mar 13;7:20.
  • Gehrke N, Biedenbach J, Huber Y, Straub BK, Galle PR, Simon P, Schattenberg JM. Voluntary exercise in mice fed an obesogenic diet alters the hepatic immune phenotype and improves metabolic parameters - an animal model of life style intervention in NAFLD. Sci Rep. 2019 Mar 8;9(1):4007.
  • Becker C, Schmidt S, Neuberger EWI, Kirsch P, Simon P, Dettweiler U. Children's Cortisol and Cell-Free DNA Trajectories in Relation to Sedentary Behavior and Physical Activity in School: A Pilot Study. Front Public Health. 2019 Feb 27;7:26.
  • Pfirrmann D, Huber Y, Schattenberg JM, Simon P. Web-Based Exercise as an Effective Complementary Treatment for Patients With Nonalcoholic Fatty Liver Disease: Intervention Study.
    J Med Internet Res. 2019 Jan 2;21(1):


  • Haller N, Ehlert T, Schmidt S, Ochmann D, Sterzing B, Grus F, Simon P. Circulation, Cell-free DNA for Monitoring Player Load in Professional Football. Int J Sports Physiol Perform. 2018 Nov 14:1-27.
  • Pfirrmann D, Simon P, Mehdorn M, Hänsig M, Stehr S, Selig L, Weimann A, Knödler M, Lordick F, Mehnert A, Gockel I. Preconditioning prior to visceral oncological surgery : A paradigm shift in visceral surgery? Chirurg. 2018 Nov;89(11):896-902.
  • Piegeler T, Stehr SN, Pfirrmann D, Knödler M, Lordick F, Mehnert A, Selig L, Weimann A, Mehdorn M, Gockel I, Simon P. Special situations of preconditioning and prehabilitation in oncological visceral surgery. Chirurg. 2018 Nov;89(11):903-908.
  • Haller N, Lorenz S, Pfirrmann D, Koch C, Lieb K, Dettweiler U, Simon P, Jung P. Individualized Web-Based Exercise for the Treatment of Depression: Randomized Controlled Trial. JMIR Ment Health. 2018 Oct 12;5(4)
  • Simon P, Neuberger EW, Wang G, Pitsiladis YP. Antidoping Science: Important Lessons From the Medical Sciences. Curr Sports Med Rep. 2018 Oct;17(10):326-331.
  • Gouveris H, Bahr K, Jahn C, Matthias C, Simon P.The Apnea-Hypopnea Index Underestimates Systemic Inflammation in Women with Sleep-Disordered Breathing. J Womens Health (Larchmt). 2018 Jul;27(7):920-926
  • Dreher M, Ehlert T, Simon P, Neuberger E.W. Boost me: Prevalence and reasons for the use of stimulant containing pre workout supplements among fitness studio visitors in Mainz (Germany) Front Psychol. 2018 Jul 17;9:1134
  • Dietz P, Quermann A, van Poppel MNM, Striegel H, Schröter H, Ulrich R, Simon P. Physical and cognitive doping in university students using the unrelated question model (UQM): Assessing the influence of the probability of receiving the sensitive question on prevalence estimation. PLoS One. 2018 May 15;13(5)
  • Pfirrmann D, Haller N, Huber Y, Jung P, Lieb K, Gockel I, Poplawska K, Schattenberg JM, Simon P. Applicability of a Web-Based, Individualized Exercise Intervention in Patients With Liver Disease, Cystic Fibrosis, Esophageal Cancer, and Psychiatric Disorders: Process Evaluation of 4 Ongoing Clinical Trials. JMIR Res Protoc. 2018 May 22;7(5)
  • Pfirrmann D, Huber Y, Schattenberg JM, Simon P. Lifestyle Change in Patients with non-alcoholic Fatty Liver Sisease (NAFLD) through an Internet-assisted Sports Intervention - The HELP Study
    INTERNIST. 2018 Apr, Volume: 59 Pages: S21-S21
  • Haller N, Helmig S, Taenny P, Petry J, Schmidt S, Simon P. Circulating, cell-free DNA as a marker for exercise load in intermittent sports. PLoS One. 2018 Jan 25;13(1)


Haller N, Simon P. Sport und Bewegung zur Therapie und Prävention. In: Andreas Fellgiebel, Martin Hautzinger (Hrsg.). Altersdepression: Ein interdisziplinäres Handbuch. Springer-Verlag.


  • Franke AG, Dietz P, Ranft K, Balló H, Simon P, Lieb K. The Use of Pharmacologic Cognitive Enhancers in Competitive Chess. Epidemiology. 2017 Nov.
  • Fleckenstein J, Simon P, König M, Vogt L, Banzer W. The pain threshold of high-threshold mechanosensitive receptors subsequent to maximal eccentric exercise is a potential marker in the prediction of DOMS associated impairment.PLoS One. 2017 Oct 6.
  • Gockel I, Pfirrmann D, Jansen-Winkeln B, Simon P.The dawning of perioperative care in esophageal cancer.J Thorac Dis. 2017 Oct;9(10):3488-3492.
  • Tug S, Tross AK, Hegen P, Neuberger EWI, Helmig S, Schöllhorn W, Simon P. Acute effects of strength exercises and effects of regular strength training on cell free DNA concentrations in blood plasma.PLoS One. 2017 Sep 14;12(9)
  • Ulrich R, Pope HG Jr, Cléret L, Petróczi A, Nepusz T, Schaffer J, Kanayama G, Comstock RD, Simon P. Doping in Two Elite Athletics Competitions Assessed by Randomized-Response Surveys.Sports Med. 2017 Aug 28.
  • Ehlert T, Tug S, Brahmer A, Neef V, Heid F, Werner C, Jansen-Winkeln B, Kneist W, Lang H, Gockel I, Simon P. Establishing PNB-qPCR for quantifying minimal ctDNA concentrations during tumour resection. Scientific Reports 7, Article number: 8876, 21. August 2017
  • Franke AG, Dietz P, Ranft K, Balló H, Simon P, Lieb K. The use of pharmacologic cognitive enhancers in competitive chess.Epidemiology. 2017 Aug 16.
  • Huber Y, Pfirrmann D, Gebhardt I, Labenz C, Simon P, Wörns M, Galle P, ...Individualisierte Sportintervention bei Patienten mit nicht-alkoholischer Fettlebererkrankung (HELP-Studie) Zeitschrift für Gastroenterologie 55 (08), FV 12
  • Huber Y, Gehrke N, Biedenbach J, Helmig S, Simon P, Straub BK, Bergheim I, Huber T, Schuppan D, Galle PR, Wörns MA, Schuchmann M, Schattenberg JM. Voluntary distance running prevents TNF-mediated liver injury in mice through alterations of the intrahepatic immune milieu. Cell Death Dis. 2017 Jun 22;8(6)
  • Endler S, Hoffmann S, Sterzing B, Simon P, Pfeiffer M. The PerPot Simulated Anaerobic Threshold-A Comparison to Typical Lactate-based Thresholds. Age (Years), 2017
  • Pfirrmann D, Tug S, Brosteanu O, Mehdorn M, Busse M, Grimminger PP, Lordick F, Glatz T, Hoeppner J, Lang H, Simon P, Gockel I. Internet-based perioperative exercise program in patients with Barrett's carcinoma scheduled for esophagectomy [iPEP - study] a prospective randomized-controlled trial.BMC Cancer. 2017 Jun 14;17(1):413.
  • Neuberger EWI, Simon P. Gene and Cell Doping: The New Frontier - Beyond Myth or Reality. Med Sport Sci. 2017 Jun 2;62:91-106.
  • Dettweiler U, Becker C, Auestad BH, Simon P, Kirsch P. Stress in School. Some Empirical Hints on the Circadian Cortisol Rhythm of Children in Outdoor and Indoor Classes. Int J Environ Res Public Health. 2017 Apr 30;14(5).


Neuberger E.W, Simon P. Genetisches Testen im Sport - Können wir schon empirische Evidenz von empirischen non-sense unterscheiden? In: S. Körner & J. Erber- Schropp (Hrsg.). Gendoping - Herausforderung für Sport und Gesellschaft. Springer Spektrum: Heidelberg.

Simon P. „Ein Stich ins Herz des Sports” - Men`sHealth, Nov.2016 (.PDF)


  • Könecke T, Primke D, Simon P. Dropout und Therapietreue von Herzpatienten in Rehabilitationssportgruppen - eine Übersicht über einschlägige Studien. Deutsche Zeitschrift für Sportmedizin 2016 Oct (10):244-248.
  • Tug S, Mehdorn M, Helmig S, Breitbach S, Ehlert T, Simon P. Exploring the Potential of cfDNA Measurements After an Exhaustive Cycle Ergometer Test as a Marker for Performance Related Parameters. Int J Sports Physiol Perform. 2016 Sep 6.
  • Zahn D, Tug S, Wenzel M, Simon P, Kubiaka T. Glucose metabolism and self-regulation - Is insulin resistance a valid proxy of self-control? Personality and Individual Differences, 99:38-45, 2016
  • Haller N, Tug S, Breitbach S, Jörgensen A, Simon P. Increases in Circulating, Cell-Free DNA During Aerobic Running Depend on Intensity and Duration. Int J Sports Physiol Perform. 2016 Sep 6.
  • Pfirrmann D, Ingelfinger P, Simon P, Tug S. Analysis of Injury Incidences in Male Professional Adult and Elite Youth Soccer Players: A Systematic Review.J Athl Train. 2016 May 31.
  • Schröter H, Studzinski B, Dietz P, Ulrich R, Striegel H, Simon P. A Comparison of the Cheater Detection and the Unrelated Question Models: A Randomized Response Survey on Physical and Cognitive Doping in Recreational Triathletes.PLoS One. 2016 May 24;11(5):e0155765.eCollection 2016.
  • Neuberger E.W, Perez I, Le Guiner C, Moser D, Ehlert T, Allais M, Moullier P, Simon P, Snyder R.O, Establishment of Two Quantitative Nested qPCR Assays Targeting the Human EPO Transgene. Gene Therapy. 2016 Apr;23(4):330-9.
  • Dietz P, Dalaker R, Letzel S, Ulrich R, Simon P. Analgesics use in competitive triathletes: its relationship to doping and on predicting its usage. J Sports Sci. 2016 Feb 25:1-5.


  • Neuberger E, Mooses M, Durussel J, Wang J, Lees M, Mooses K, Brahmer A, Wang G, Pitsiladis Y, Simon P. Small RNA sequencing of red blood cell specific miRNAs reveals expression changes after 6 weeks of recombinant EPO (rEPO) administration in healthy recreational athletes : American Journal of Hematology, Volume: 90,Issue: 8,Pages: E171-E171,Pub: Aug 2015
  • Frühbeis C, Helmig S, Tug S, Simon P, Krämer-Albers EM. Physical exercise induces rapid release of small extracellular vesicles into the circulation. J Extracell Vesicles. 2015 Jul 2;4:28239. eCollection 2015
  • Helmig S, Frühbeis C, Krämer-Albers EM, Simon P, Tug S. Release of bulk cell free DNA during physical exercise occurs independent of extracellular vesicles.Eur J Appl Physiol. 2015 Nov;115(11):2271-80.Epub 2015 Jul 1.
  • Tug S, Helmig S, Deichmann ER, Schmeier-Jürchott A, Wagner E, Zimmermann T, Radsak M, Giacca M, Simon P. Exercise-induced increases in cell free DNA in human plasma originate predominantly from cells of the haematopoietic lineage. Exerc Immunol Rev. 2015;21:164-173.
  • Dettweiler U, Unlu A, Lauterbach G, Legl A, Simon P, Kugelmann C. Alien at home: Adjustment strategies of students returning from a six-months over-sea's educational programme. International Journal of Intercultural Relations, Jan 2015; Volume: 44, Pages: 72-87.


  • Moser DA, Braga L, Raso A, Zacchigna S, Giacca M, Simon P. Transgene Detection by Digital Droplet PCR. PLoS One. 2014 Nov 6;9(11):e111781. eCollection 2014.
  • Tug S, Helmig S, Menke J, Zahn D, Kubiak T, Schwarting A, Simon P.Correlation between cell free DNA levels and medical evaluation of disease progression in systemic lupus erythematosus patients. Cell Immunol. 2014 Aug 20;292(1-2):32-39.
  • Hoffmann SW, Tug S, Simon P. Child-caregivers' body weight and habitual physical activity status is associated with overweight in kindergartners. BMC Public Health. 2014 Aug 9;14:822
  • Breitbach S, Tug S, Simon P. Conventional and Genetic Talent Identification in Sports: Will Recent Developments Trace Talent? Sports Med. 2014 Jul 12.
  • Dietz P, Ulrich R, Niess A, Best R, Simon P, Striegel H. Prediction Profiles for Nutritional Supplement Use Among Young German Elite Athletes. Int J Sport Nutr Exerc Metab. 2014 Jun 5.
  • Breitbach S, Sterzing B, Magallanes C, Tug S, Simon P.Direct measurement of cell-free DNA from serially collected capillary plasma during incremental exercise. J Appl Physiol (1985). 2014 Jul 15;117(2):119-30.
  • Neuberger E, Simon P. Auf der Suche nach geeigneten Nachweismethoden für Doping - das Transkriptom. Dtsch Z Sportmed. 2014; 65: 272-278.
  • Breitbach S, Tug S, Helmig S, Zahn D, Kubiak T, Michal M, Gori T, Ehlert T, Beiter T, Simon P. Direct quantification of cell-free, circulating DNA from unpurified Plasma. PLoS One. 2014 Mar 3;9(3):e87838. eCollection 2014
  • Wang G, Neuberger E, Perikles S, Durussel J, McClure JD, McBride MW, Pitsiladis YP.Circulating microRNAs as biomarkers for recombinant human erythropoietin (r-HuEPO) doping detection. Acta Physiologica, Mar 2014; Volume: 210, Pages: 138-140, Supplement: 695.


  • Dietz P, Ulrich R, Dalaker R, Striegel H, Franke AG, Lieb K, Simon P. Associations between Physical and Cognitive Doping - A Cross-Sectional Study in 2.997 Triathletes. PLoS One. 2013 Nov 13;8(11):e78702.
  • Best R, Simon P, Niess AM, Striegel H. Influence of various preseason training in elite youth soccer player. Central European Journal of Medicine. 2013 Nov;
  • Goeppert B, Schmidt CR, Geiselhart L, Dutruel C, Capper D, Renner M, Vogel MN, Zachskorn C, Zinke J, Campos B, Schmezer P, Popanda O, Wick W, Weller M, Meyermann R, Schittenhelm J, Harter PN, Simon P, Weichert W, Schirmacher P, Plass C, Mittelbronn M. Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation. J Neuropathol Exp Neurol. 2013 Oct;72(10):933-41.
  • Hoffmann SW, Tug S, Simon P. Obesity prevalence and unfavorable health risk behaviors among German kindergarten teachers: cross-sectional results of the kindergarten teacher health study. BMC Public Health. 2013 Oct 4;13(1):927.
  • Michal M, Simon P, Gori T, König J, Wild PS, Wiltink J, Tug S, Sterzing B, Unterrainer J, Münzel T, Beutel ME. Psychodynamic Motivation and Training program (PMT) for the secondary prevention in patients with stable coronary heart disease: study protocol for a randomized controlled trial of feasibility and effects. Trials. 2013 Sep 25;14(1):314.
  • Giel KE, Zipfel S, Schweizer R, Braun R, Ranke MB, Binder G, Ehehalt S, DISKUS Study Group. Eating disorder pathology in adolescents participating in a lifestyle intervention for obesity: associations with weight change, general psychopathology and health-related quality of life. Obes Facts. 2013;6(4):307-16. Epub 2013 Aug 7.
  • Franke AG, Bagusat C, Dietz P, Hoffmann I, Simon P, Ulrich R, Lieb K. Use of illicit and prescription drugs for cognitive or mood enhancement among surgeons. BMC Med. 2013 Apr 9;11(1):102.
  • Dietz P, Striegel H, Franke AG, Lieb K, Simon P, Ulrich R. Randomized response estimates for the 12-month prevalence of cognitive-enhancing drug use in university students. Pharmacotherapy. 2013 Jan;33(1):44-50.
  • Ehlert T, Simon P, Moser DA. Epigenetics in sports.Sports Med. 2013 Feb;43(2):93-110.


  • Ernst S, Simon P. A quantitative approach for assessing significant improvements in elite sprint performance: Has IGF-1 entered the arena? Drug Test Anal. 2012 Aug 29.
  • Ulrich R, Schröter H, Striegel H, Simon P. Asking Sensitive Questions: A Statistical Power Analysis of Randomized Response Models. Psychol Methods. 2012 Aug 27.
  • Springer F, Ehehalt S, Sommer J, Ballweg V, Machann J, Binder G, Claussen CD, Schick F, DISKUS-Study Group. Predicting volumes of metabolically important whole-body adipose tissue compartments in overweight and obese adolescents by different MRI approaches and anthropometry. Eur J Radiol. 2012 Jul;81(7):1488-94.
  • Hoffmann S, Ulrich R, Simon P. Refined analysis of the critical age ranges of childhood overweight - implications for primary prevention. Obesity (Silver Spring). 2012 Jun 20.
  • Breitbach S, Tug S, Simon P. Circulating cell-free DNA: An up-coming molecular marker in exercise physiology, Sports Med. 2012 Jul 1;42(7):565-86.
  • Dietz P, Hoffmann S, Lachtermann E, Simon P. The influence of exclusive resistance training on body composition and cardiovascular risk factors in overweight or obese children: a systematic review, Obesity Facts 2012 Jul 27;5(4):546-560.
  • Moser DA, Neuberger EW, Simon P. A quick one-tube nested PCR-protocol for EPO transgene detection. Drug Test Anal. 2012 Nov;4(11):870-5.
  • Neuberger EW, Jurkiewicz M, Moser DA, Simon P. Detection of EPO gene doping in blood. Drug Test Anal. 2012 Apr 17.
  • Schum J, Blumenstock G, Weber K, Schweizer R, Pfaff C, Schurr N, Ranke MB, Binder G, Ehehalt S, DISKUS-Study Group. Variants of the FTO Gene in Obese Children and their Impact on Body Composition and Metabolism before and after Lifestyle Intervention. Exp Clin Endocrinol Diabetes. 2012 Mar;120(3):128-31.
  • Tug S, Lauer U, Simon P. Gendoping- Nachweis prinzipiell möglich, Dtsch Arztebl 2012; 109(3): A-80 / B-76 / C-76.
  • Kuschel A, Simon P, Tug S Functional regulation of HIF-1alpha under normoxia - is there more than post-translational regulation? Journal of cellular physiology. 2012 Feb;227(2):514-24.
  • Breitbach S. Talentauswahl im Sport mittels genetischer Selektion, molekularer Diagnostik oder Sichtung: Enhancement durch Selektion? Sammelband "Höher - schneller -weiter. Gentechnologisches Enhancement im Spitzensport". mentis Verlag, 2012
  • Breitbach S, Beiter T, Hudemann J, Striegel H, Simon P. Circulating, cell-free DNA concentrations in human plasma of soccer players before and after a typical soccer training session. Acta Physiologica, 2012.


  • Breitbach S, Bohringer A, Simon P, Tug S. The differential expression of several mRNA variants of HIF1a during endurance exercise and under normobar hypoxia. Acta Physiologica 2011; Volume 201, Supplement 682 The 90th Annual Meeting of The German Physiological Society 26/03/2011-29/03/2011 Regensburg, Germany
  • Neuberger EW, Moser DA, Simon P. Principle considerations for the use of transcriptomics in doping research. Drug Test Anal. 2011 Oct;3(10):668-75.
  • Ehehalt S, Binder G, Schurr N, Pfaff C, Ranke MB, Schweizer R; DISKUS-Study Group. The functional muscle-bone unit in obese children - altered bone structure leads to normal strength strain index. Exp Clin Endocrinol Diabetes. 2011 Jun;119(6):321-6.
  • Springer F, Ehehalt S, Sommer J, Ballweg V, Machann J, Binder G, Claussen CD, Schick F; DISKUS-Study Group. Assessment of relevant hepatic steatosis in obeseadolescents by rapid fat-selective GRE imaging with spatial-spectral excitation: a quantitative comparison with spectroscopic findings. Eur Radiol. 2011 Apr;21(4):816-22.
  • Beiter T, Fragasso A, Hudemann J, Nieß AM, Simon P. Short-Term Treadmill Running as a Model for Studying Cell-Free DNA Kinetics In Vivo. Clin Chem. 2011 Apr;57(4):633-636.
  • Beiter T, Zimmermann M, Fragasso A, Hudemann J, Niess AM, Bitzer M, Lauer UM, Simon P. Direct and long-term detection of gene doping in conventional blood samples. Gene Ther. 2011 Mar;18(3):225-31.
  • Nolte A, Secker S, Walker T, Greiner TO, Neumann B, Simon P, Ziemer G, Wendel HP. Veins are no arteries: even moderate arterial pressure induces significant adhesion molecule expression of vein grafts in an ex vivo circulation model. J Cardiovasc Surg (Torino). 2011 Apr;52(2):251-9.
  • Walsh NP, Gleeson M, Shephard RJ, Gleeson M, Woods JA, Bishop NC, Fleshner M, Green C, Pedersen BK, Hoffman-Goetz L, Rogers CJ, Northoff H, Abbasi A, Simon P. Position statement. Part one: Immune function and exercise. Exerc Immunol Rev. 2011;17:6-63. Review.
  • Schittenhelm J, Simon P, Harter PN, Zachskorn C, Schlaszus H, Röttger F,Winkels M, Weller M, Meyermann R, Mittelbronn M. CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms. Histopathology. 2011 Apr;58(5):739-49.
  • Ehehalt S, Schweizer R, Blumenstock G, Pfaff C, Schurr N, Weber K, Ranke MB, Binder G; DISKUS-Study Group. Investigation of myostatin serum levels before and after a 6-month lifestyle intervention program in obese children. Exp Clin Endocrinol Diabetes. 2011 Apr;119(4):238-42.
  • Ehlert T, Simon P Genetik und Epigenetik der körperlichen Leistungsfähigkeit
  • Breitbach S. Genetische und molekulare Tests am Athleten. Medical Sports Network 1/2011


  • Waalkes S, Simon P, Hennenlotter J, Knapp J, Tezval H, Serth J, Stenzl A, Kuczyk MA, Merseburger AS. Altered expression of Akt signaling pathway parameters in prostate needle biopsies derived from benign, adjacent and cancerous tissue.Oncol Rep. 2010 May;23(5):1257-60.
  • Ehlert T, Simon P, Tug S. Misleading interpretations and public misinformation on human growth hormone in athletes. Ann Intern Med. 2010 Sep 7;153(5):345-6
  • Ciobanu DC, Lu L, Mozhui K, Wang X, Jagalur M, Morris JA, Taylor WL, Dietz K, Simon P, Williams RW. Detection, validation, and downstream analysis of allelic variation in gene expression. Genetics. 2010 Jan;184(1):119-28.
  • Striegel H, Ulrich R, Simon P. Randomized response estimates for doping and illicit drug use in elite athletes. Drug Alcohol Depend. 2010 Jan 15;106(2-3):230-2.
  • Lehmann R, Zhao X, Weigert C, Simon P, Fehrenbach E, Fritsche J, Machann J, Schick F, Wang J, Hoene M, Schleicher ED, Häring HU, Xu G, Niess AM. Medium Chain Acylcarnitines Dominate the Metabolite Pattern in Humans under Moderate Intensity Exercise and Support Lipid Oxidation. 2010 Juli;


  • Schaible E, Boehringer A, Callau D, Niess AM, Simon P. Exercise and menstrual cycle dependent expression of a truncated alternative splice variant of Hif1alpha in leukocytes.Exerc Immunol Rev. 2009;15:145-56.
  • Hansel J, Simon P. Letter by Hansel and Simon regarding article, "Body mass index and vigorous physical activity and the risk of heart failure among men".Circulation. 2009 Sep 15;120(11):e90; author reply e91.
  • Avci-Adali M, Nolte A, Simon P, Ziemer G, Wendel HP. Porcine EPCs downregulate stem cell markers and upregulate endothelial maturation markers during in vitro cultivation. J Tissue Eng Regen Med. 2009 Oct;3(7):512-20.
  • Nolte A, Raabe C, Walker T, Simon P, Ziemer G, Wendel HP. Optimized basic conditions are essential for successful siRNA transfection into primary endothelial cells. Oligonucleotides. 2009 Jun;19(2):141-50.
  • Hansel J, Solleder I, Gfroerer W, Muth CM, Paulat K, Simon P, Heitkamp HC, Niess A, Tetzlaff K. Hypoxia and cardiac arrhythmias in breath-hold divers during voluntary immersed breath-holds. Eur J Appl Physiol. 2009 Mar;105(5):673-8.
  • Mittelbronn M, Harter P, Warth A, Lupescu A, Schilbach K, Vollmann H, Capper D, Goeppert B, Frei K, Bertalanffy H, Weller M, Meyermann R, Lang F, Simon P. EGR-1 is regulated by N-methyl-D-aspartate-receptor stimulation and associated with patient survival in human high grade astrocytomas. Brain Pathol. 2009 Apr;19(2):195-204.


  • Beiter T, Zimmermann M, Fragasso A, Armeanu S, Lauer UM, Bitzer M, Su H, Young WL, Niess AM, Simon P. Establishing a novel single-copy primer-internal intron-spanning PCR (spiPCR) procedure for the direct detection of gene doping. Exerc Immunol Rev. 2008;14:73-85. Beschreibung des Verfahrens:

Veröffentlichte Patentanmeldung:

(WO/2007/124861) Detection of Transgenic DNA (tDNA), PCT/EP2007/003385