Publikationen

Prof. Dr. Dr. P.Simon 

Dr. E. Lachtermann 

2015 2014 2013 2012 2011 2010 2009 2008

2017

  • Franke AG, Dietz P, Ranft K, Balló H, Simon P, Lieb K. The Use of Pharmacologic Cognitive Enhancers in Competitive Chess. Epidemiology. 2017 Nov;28(6):e57-e58.
  • Fleckenstein J, Simon P, König M, Vogt L, Banzer W. The pain threshold of high-threshold mechanosensitive receptors subsequent to maximal eccentric exercise is a potential marker in the prediction of DOMS associated impairment.PLoS One. 2017 Oct 6;12(10):e0185463
  • Tug S, Tross AK, Hegen P, Neuberger EWI, Helmig S, Schöllhorn W, Simon P. Acute effects of strength exercises and effects of regular strength training on cell free DNA concentrations in blood plasma.PLoS One. 2017 Sep 14;12(9)
  • Ulrich R, Pope HG Jr, Cléret L, Petróczi A, Nepusz T, Schaffer J, Kanayama G, Comstock RD, Simon P. Doping in Two Elite Athletics Competitions Assessed by Randomized-Response Surveys.Sports Med. 2017 Aug 28.
  • Ehlert T, Tug S, Brahmer A, Neef V, Heid F, Werner C, Jansen-Winkeln B, Kneist W, Lang H, Gockel I, Simon P. Establishing PNB-qPCR for quantifying minimal ctDNA concentrations during tumour resection. Scientific Reports 7, Article number: 8876, 21. August 2017
  • Franke AG, Dietz P, Ranft K, Balló H, Simon P, Lieb K. The use of pharmacologic cognitive enhancers in competitive chess.Epidemiology. 2017 Aug 16.
  • Huber Y, Pfirrmann D, Gebhardt I, Labenz C, Simon P, Wörns M, Galle P, ...Individualisierte Sportintervention bei Patienten mit nicht-alkoholischer Fettlebererkrankung (HELP-Studie) Zeitschrift für Gastroenterologie 55 (08), FV 12
  • Huber Y, Gehrke N, Biedenbach J, Helmig S, Simon P, Straub BK, Bergheim I, Huber T, Schuppan D, Galle PR, Wörns MA, Schuchmann M, Schattenberg JM. Voluntary distance running prevents TNF-mediated liver injury in mice through alterations of the intrahepatic immune milieu. Cell Death Dis. 2017 Jun 22;8(6)
  • Endler S, Hoffmann S, Sterzing B, Simon P, Pfeiffer M. The PerPot Simulated Anaerobic Threshold–A Comparison to Typical Lactate-based Thresholds. Age (Years), 2017  
  • Pfirrmann D, Tug S, Brosteanu O, Mehdorn M, Busse M, Grimminger PP, Lordick F, Glatz T, Hoeppner J, Lang H, Simon P, Gockel I. Internet-based perioperative exercise program in patients with Barrett's carcinoma scheduled for esophagectomy [iPEP - study] a prospective randomized-controlled trial.BMC Cancer. 2017 Jun 14;17(1):413.
  • Neuberger EWI, Simon P. Gene and Cell Doping: The New Frontier - Beyond Myth or Reality. Med Sport Sci. 2017 Jun 2;62:91-106.
  • Dettweiler U, Becker C, Auestad BH, Simon P, Kirsch P. Stress in School. Some Empirical Hints on the Circadian Cortisol Rhythm of Children in Outdoor and Indoor Classes. Int J Environ Res Public Health. 2017 Apr 30;14(5).

2016

  • Simon P. „Ein Stich ins Herz des Sports“ Interview - Men`sHealth, Nov.2016 (.PDF)
  • Könecke T, Primke D, Simon P. Dropout und Therapietreue von Herzpatienten in Rehabilitationssportgruppen – eine Übersicht über einschlägige Studien. Deutsche Zeitschrift für Sportmedizin 2016 Oct (10):244-248.
  • Tug S, Mehdorn M, Helmig S, Breitbach S, Ehlert T, Simon P. Exploring the Potential of cfDNA Measurements After an Exhaustive Cycle Ergometer Test as a Marker for Performance Related Parameters. Int J Sports Physiol Perform. 2016 Sep 6.
  • Zahn D, Tug S, Wenzel M, Simon P, Kubiaka T. Glucose metabolism and self-regulation - Is insulin resistance a valid proxy of self-control? Personality and Individual Differences, 99:38-45, 2016
  • Haller N, Tug S, Breitbach S, Jörgensen A, Simon P. Increases in Circulating, Cell-Free DNA During Aerobic Running Depend on Intensity and Duration. Int J Sports Physiol Perform. 2016 Sep 6.
  • Pfirrmann D, Ingelfinger P, Simon P, Tug S. Analysis of Injury Incidences in Male Professional Adult and Elite Youth Soccer Players: A Systematic Review.J Athl Train. 2016 May 31.
  • Schröter H, Studzinski B, Dietz P, Ulrich R, Striegel H, Simon P. A Comparison of the Cheater Detection and the Unrelated Question Models: A Randomized Response Survey on Physical and Cognitive Doping in Recreational Triathletes.PLoS One. 2016 May 24;11(5):e0155765.eCollection 2016.
  • Neuberger E.W, Perez I, Le Guiner C, Moser D, Ehlert T, Allais M, Moullier P, Simon P, Snyder R.O, Establishment of Two Quantitative Nested qPCR Assays Targeting the Human EPO Transgene. Gene Therapy. 2016 Apr;23(4):330-9.
  • Dietz P, Dalaker R, Letzel S, Ulrich R, Simon P. Analgesics use in competitive triathletes: its relationship to doping and on predicting its usage. J Sports Sci. 2016 Feb 25:1-5.

2015

  • Neuberger E, Mooses M, Durussel J, Wang J, Lees M, Mooses K, Brahmer A, Wang G, Pitsiladis Y, Simon P. Small RNA sequencing of red blood cell specific miRNAs reveals expression changes after 6 weeks of recombinant EPO (rEPO) administration in healthy recreational athletes : American Journal of Hematology, Volume: 90,Issue: 8,Pages: E171-E171,Pub: Aug 2015
  • Frühbeis C, Helmig S, Tug S, Simon P, Krämer-Albers EM. Physical exercise induces rapid release of small extracellular vesicles into the circulation. J Extracell Vesicles. 2015 Jul 2;4:28239. eCollection 2015 
  • Helmig S, Frühbeis C, Krämer-Albers EM, Simon P, Tug S. Release of bulk cell free DNA during physical exercise occurs independent of extracellular vesicles.Eur J Appl Physiol. 2015 Nov;115(11):2271-80.Epub 2015 Jul 1.
  • Tug S, Helmig S, Deichmann ER, Schmeier-Jürchott A, Wagner E, Zimmermann T, Radsak M, Giacca M, Simon P. Exercise-induced increases in cell free DNA in human plasma originate predominantly from cells of the haematopoietic lineage. Exerc Immunol Rev. 2015;21:164-173.
  • Dettweiler U, Unlu A, Lauterbach G, Legl A, Simon P, Kugelmann C. Alien at home: Adjustment strategies of students returning from a six-months over-sea's educational programme. International Journal of Intercultural Relations, Jan 2015; Volume: 44, Pages: 72-87.

2014

  • Moser DA, Braga L, Raso A, Zacchigna S, Giacca M, Simon P. Transgene Detection by Digital Droplet PCR. PLoS One. 2014 Nov 6;9(11):e111781. eCollection 2014.
  • Tug S, Helmig S, Menke J, Zahn D, Kubiak T, Schwarting A, Simon P.Correlation between cell free DNA levels and medical evaluation of disease progression in systemic lupus erythematosus patients. Cell Immunol. 2014 Aug 20;292(1-2):32-39.
  • Hoffmann SW, Tug S, Simon P. Child-caregivers' body weight and habitual physical activity status is associated with overweight in kindergartners. BMC Public Health. 2014 Aug 9;14:822
  • Breitbach S, Tug S, Simon P. Conventional and Genetic Talent Identification in Sports: Will Recent Developments Trace Talent? Sports Med. 2014 Jul 12.   
  • Dietz P, Ulrich R, Niess A, Best R, Simon P, Striegel H. Prediction Profiles for Nutritional Supplement Use Among Young German Elite Athletes. Int J Sport Nutr Exerc Metab. 2014 Jun 5.
  • Breitbach S, Sterzing B, Magallanes C, Tug S, Simon P.Direct measurement of cell-free DNA from serially collected capillary plasma during incremental exercise. J Appl Physiol (1985). 2014 Jul 15;117(2):119-30.
  • Neuberger E, Simon P. Auf der Suche nach geeigneten Nachweismethoden für Doping – das Transkriptom. Dtsch Z Sportmed. 2014; 65: 272-278.
  • Breitbach S, Tug S, Helmig S, Zahn D, Kubiak T, Michal M, Gori T, Ehlert T, Beiter T, Simon P. Direct quantification of cell-free, circulating DNA from unpurified Plasma. PLoS One. 2014 Mar 3;9(3):e87838. eCollection 2014
  • Wang G, Neuberger E, Perikles S, Durussel J, McClure JD, McBride MW,  Pitsiladis YP.Circulating microRNAs as biomarkers for recombinant human erythropoietin (r-HuEPO) doping detection. Acta Physiologica, Mar 2014; Volume: 210, Pages: 138-140, Supplement: 695.

2013

  • Dietz P, Ulrich R, Dalaker R, Striegel H, Franke AG, Lieb K, Simon P. Associations between Physical and Cognitive Doping - A Cross-Sectional Study in 2.997 Triathletes. PLoS One. 2013 Nov 13;8(11):e78702.
  • Best R, Simon P, Niess AM, Striegel H. Influence of various preseason training in elite youth soccer player. Central European Journal of Medicine. 2013 Nov;
  • Goeppert B, Schmidt CR, Geiselhart L, Dutruel C, Capper D, Renner M, Vogel MN, Zachskorn C, Zinke J, Campos B, Schmezer P, Popanda O, Wick W, Weller M, Meyermann R, Schittenhelm J, Harter PN, Simon P, Weichert W, Schirmacher P, Plass C, Mittelbronn M. Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation. J Neuropathol Exp Neurol. 2013 Oct;72(10):933-41.
  • Hoffmann SW, Tug S, Simon P. Obesity prevalence and unfavorable health risk behaviors among German kindergarten teachers: cross-sectional results of the kindergarten teacher health study. BMC Public Health. 2013 Oct 4;13(1):927.
  • Michal M, Simon P, Gori T, König J, Wild PS, Wiltink J, Tug S, Sterzing B, Unterrainer J, Münzel T, Beutel ME. Psychodynamic Motivation and Training program (PMT) for the secondary prevention in patients with stable coronary heart disease: study protocol for a randomized controlled trial of feasibility and effects. Trials. 2013 Sep 25;14(1):314.
  • Giel KE, Zipfel S, Schweizer R, Braun R, Ranke MB, Binder G, Ehehalt S, DISKUS Study Group. Eating disorder pathology in adolescents participating in a lifestyle intervention for obesity: associations with weight change, general psychopathology and health-related quality of life. Obes Facts. 2013;6(4):307-16. Epub 2013 Aug 7.
  • Franke AG, Bagusat C, Dietz P, Hoffmann I, Simon P, Ulrich R, Lieb K. Use of illicit and prescription drugs for cognitive or mood enhancement among surgeons. BMC Med. 2013 Apr 9;11(1):102.
  • Dietz P, Striegel H, Franke AG, Lieb K, Simon P, Ulrich R. Randomized response estimates for the 12-month prevalence of cognitive-enhancing drug use in university students. Pharmacotherapy. 2013 Jan;33(1):44-50.
  • Ehlert T, Simon P, Moser DA. Epigenetics in sports.Sports Med. 2013 Feb;43(2):93-110.

2012

  • Ernst S, Simon P. A quantitative approach for assessing significant improvements in elite sprint performance: Has IGF-1 entered the arena? Drug Test Anal. 2012 Aug 29. 
  • Ulrich R, Schröter H, Striegel H, Simon P. Asking Sensitive Questions: A Statistical Power Analysis of Randomized Response Models. Psychol Methods. 2012 Aug 27.
  • Springer F, Ehehalt S, Sommer J, Ballweg V, Machann J, Binder G, Claussen CD, Schick F, DISKUS-Study Group. Predicting volumes of metabolically important whole-body adipose tissue compartments in overweight and obese adolescents by different MRI approaches and anthropometry. Eur J Radiol. 2012 Jul;81(7):1488-94.  
  • Hoffmann S, Ulrich R, Simon P. Refined analysis of the critical age ranges of childhood overweight - implications for primary prevention. Obesity (Silver Spring). 2012 Jun 20.
  • Breitbach S, Tug S, Simon P. Circulating cell-free DNA: An up-coming molecular marker in exercise physiology, Sports Med. 2012 Jul 1;42(7):565-86.
  • Dietz P, Hoffmann S, Lachtermann E, Simon P. The influence of exclusive resistance training on body composition and cardiovascular risk factors in overweight or obese children: a systematic review, Obesity Facts 2012 Jul 27;5(4):546-560.             
  • Moser DA, Neuberger EW, Simon P. A quick one-tube nested PCR-protocol for EPO transgene detection. Drug Test Anal. 2012 Nov;4(11):870-5.
  • Neuberger EW, Jurkiewicz M, Moser DA, Simon P. Detection of EPO gene doping in blood. Drug Test Anal. 2012 Apr 17. 
  • Schum J, Blumenstock G, Weber K, Schweizer R, Pfaff C, Schurr N, Ranke MB, Binder G, Ehehalt S, DISKUS-Study Group. Variants of the FTO Gene in Obese Children and their Impact on Body Composition and Metabolism before and after Lifestyle Intervention. Exp Clin Endocrinol Diabetes. 2012 Mar;120(3):128-31.
  • Tug S, Lauer U, Simon P. Gendoping- Nachweis prinzipiell möglich, Dtsch Arztebl 2012; 109(3): A-80 / B-76 / C-76.
  • Kuschel A, Simon P, Tug S Functional regulation of HIF-1alpha under normoxia - is there more than post-translational regulation? Journal of cellular physiology. 2012 Feb;227(2):514-24.
  • Breitbach S. Talentauswahl im Sport mittels genetischer Selektion, molekularer Diagnostik oder Sichtung: Enhancement durch Selektion? Sammelband "Höher - schneller -weiter. Gentechnologisches Enhancement im Spitzensport". mentis Verlag, 2012
  • Breitbach S, Beiter T, Hudemann J, Striegel H, Simon P. Circulating, cell-free DNA concentrations in human plasma of soccer players before and after a typical soccer training session. Acta Physiologica, 2012.

2011

  • Breitbach S, Bohringer A, Simon P, Tug S. The differential expression of several mRNA variants of HIF1a during endurance exercise and under normobar hypoxia. Acta Physiologica 2011; Volume 201, Supplement 682 The 90th Annual Meeting of The German Physiological Society 26/03/2011-29/03/2011 Regensburg, Germany
  • Neuberger EW, Moser DA, Simon P. Principle considerations for the use of transcriptomics in doping research. Drug Test Anal. 2011 Oct;3(10):668-75.
  • Ehehalt S, Binder G, Schurr N, Pfaff C, Ranke MB, Schweizer R; DISKUS-Study Group. The functional muscle-bone unit in obese children - altered bone structure leads to normal strength strain index. Exp Clin Endocrinol Diabetes. 2011 Jun;119(6):321-6.  
  • Springer F, Ehehalt S, Sommer J, Ballweg V, Machann J, Binder G, Claussen CD, Schick F; DISKUS-Study Group. Assessment of relevant hepatic steatosis in obeseadolescents by rapid fat-selective GRE imaging with spatial-spectral excitation: a quantitative comparison with spectroscopic findings. Eur Radiol. 2011 Apr;21(4):816-22.
  • Beiter T, Fragasso A, Hudemann J, Nieß AM, Simon P. Short-Term Treadmill Running as a Model for Studying Cell-Free DNA Kinetics In Vivo. Clin Chem. 2011 Apr;57(4):633-636.
  • Beiter T, Zimmermann M, Fragasso A, Hudemann J, Niess AM, Bitzer M, Lauer UM, Simon P. Direct and long-term detection of gene doping in conventional blood samples. Gene Ther. 2011 Mar;18(3):225-31.
  • Nolte A, Secker S, Walker T, Greiner TO, Neumann B, Simon P, Ziemer G, Wendel HP. Veins are no arteries: even moderate arterial pressure induces significant adhesion molecule expression of vein grafts in an ex vivo circulation model. J Cardiovasc Surg (Torino). 2011 Apr;52(2):251-9.  
  • Walsh NP, Gleeson M, Shephard RJ, Gleeson M, Woods JA, Bishop NC, Fleshner M, Green C, Pedersen BK, Hoffman-Goetz L, Rogers CJ, Northoff H, Abbasi A, Simon P. Position statement. Part one: Immune function and exercise. Exerc Immunol Rev. 2011;17:6-63. Review. 
  • Schittenhelm J, Simon P, Harter PN, Zachskorn C, Schlaszus H, Röttger F,Winkels M, Weller M, Meyermann R, Mittelbronn M. CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms. Histopathology. 2011 Apr;58(5):739-49.
  • Ehehalt S, Schweizer R, Blumenstock G, Pfaff C, Schurr N, Weber K, Ranke MB, Binder G; DISKUS-Study Group. Investigation of myostatin serum levels before and after a 6-month lifestyle intervention program in obese children. Exp Clin Endocrinol Diabetes. 2011 Apr;119(4):238-42. 
  • Ehlert T, Simon P Genetik und Epigenetik der körperlichen Leistungsfähigkeit www.zeitschrift-sportmedizin.de 
  • Breitbach S. Genetische und molekulare Tests am Athleten. Medical Sports Network 1/2011

2010

  • Waalkes S, Simon P, Hennenlotter J, Knapp J, Tezval H, Serth J, Stenzl A, Kuczyk MA, Merseburger AS. Altered expression of Akt signaling pathway parameters in prostate needle biopsies derived from benign, adjacent and cancerous tissue.Oncol Rep. 2010 May;23(5):1257-60.
  • Ehlert T, Simon P, Tug S. Misleading interpretations and public misinformation on human growth hormone in athletes. Ann Intern Med. 2010 Sep 7;153(5):345-6
  • Ciobanu DC, Lu L, Mozhui K, Wang X, Jagalur M, Morris JA, Taylor WL, Dietz K, Simon P, Williams RW. Detection, validation, and downstream analysis of allelic variation in gene expression. Genetics. 2010 Jan;184(1):119-28.
  • Striegel H, Ulrich R, Simon P. Randomized response estimates for doping and illicit drug use in elite athletes. Drug Alcohol Depend. 2010 Jan 15;106(2-3):230-2.
  • Lehmann R, Zhao X, Weigert C, Simon P, Fehrenbach E, Fritsche J, Machann J, Schick F, Wang J, Hoene M, Schleicher ED, Häring HU, Xu G, Niess AM. Medium Chain Acylcarnitines Dominate the Metabolite Pattern in Humans under Moderate Intensity Exercise and Support Lipid Oxidation. 2010 Juli; http://www.plosone.org/article/

2009

  • Schaible E, Boehringer A, Callau D, Niess AM, Simon P. Exercise and menstrual cycle dependent expression of a truncated alternative splice variant of Hif1alpha in leukocytes.Exerc Immunol Rev. 2009;15:145-56.
  • Hansel J, Simon P. Letter by Hansel and Simon regarding article, "Body mass index and vigorous physical activity and the risk of heart failure among men".Circulation. 2009 Sep 15;120(11):e90; author reply e91.  
  • Avci-Adali M, Nolte A, Simon P, Ziemer G, Wendel HP. Porcine EPCs downregulate stem cell markers and upregulate endothelial maturation markers during in vitro cultivation. J Tissue Eng Regen Med. 2009 Oct;3(7):512-20. 
  • Nolte A, Raabe C, Walker T, Simon P, Ziemer G, Wendel HP. Optimized basic conditions are essential for successful siRNA transfection into primary endothelial cells. Oligonucleotides. 2009 Jun;19(2):141-50. 
  • Hansel J, Solleder I, Gfroerer W, Muth CM, Paulat K, Simon P, Heitkamp HC, Niess A, Tetzlaff K. Hypoxia and cardiac arrhythmias in breath-hold divers during voluntary immersed breath-holds. Eur J Appl Physiol. 2009 Mar;105(5):673-8. 
  • Mittelbronn M, Harter P, Warth A, Lupescu A, Schilbach K, Vollmann H, Capper D, Goeppert B, Frei K, Bertalanffy H, Weller M, Meyermann R, Lang F, Simon P. EGR-1 is regulated by N-methyl-D-aspartate-receptor stimulation and associated with patient survival in human high grade astrocytomas. Brain Pathol. 2009 Apr;19(2):195-204.

2008

  • Beiter T, Zimmermann M, Fragasso A, Armeanu S, Lauer UM, Bitzer M, Su H, Young WL, Niess AM, Simon P. Establishing a novel single-copy primer-internal intron-spanning PCR (spiPCR) procedure for the direct detection of gene doping. Exerc Immunol Rev. 2008;14:73-85. Beschreibung des Verfahrens: http://www.medizin.uni-tuebingen.de

Veröffentlichte Patentanmeldung:

(WO/2007/124861) Detection of Transgenic DNA (tDNA), PCT/EP2007/003385 www.wipo.int