Publikationen - Prof. Dr. Dr. Perikles Simon


2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2001 1999 1998 Übersichtsarbeiten Applications for Patents Dissertationen


  • Pfirrmann D, Ingelfinger P, Simon P, Tug S. Analysis of Injury Incidences in Male Professional Adult and Elite Youth Soccer Players: A Systematic Review.J Athl Train. 2016 May 31.
  • Schröter H, Studzinski B, Dietz P, Ulrich R, Striegel H, Simon P. A Comparison of the Cheater Detection and the Unrelated Question Models: A Randomized Response Survey on Physical and Cognitive Doping in Recreational Triathletes.PLoS One. 2016 May 24;11(5):e0155765.eCollection 2016.
  • Dietz P, Dalaker R, Letzel S, Ulrich R, Simon P. Analgesics use in competitive triathletes: its relationship to doping and on predicting its usage. J Sports Sci. 2016 Feb 25:1-5. [Epub ahead of print] 


  • Neuberger E, Mooses M, Durussel J, Wang J, Lees M, Mooses K, Brahmer A, Wang G, Pitsiladis Y, Simon P. Small RNA sequencing of red blood cell specific miRNAs reveals expression changes after 6 weeks of recombinant EPO (rEPO) administration in healthy recreational athletes : American Journal of Hematology, Volume: 90,Issue: 8,Pages: E171-E171,Pub: Aug 2015
  • Frühbeis C, Helmig S, Tug S, Simon P, Krämer-Albers EM. Physical exercise induces rapid release of small extracellular vesicles into the circulation. J Extracell Vesicles. 2015 Jul 2;4:28239. eCollection 2015
  • Helmig S, Frühbeis C, Krämer-Albers EM, Simon P, Tug S. Release of bulk cell free DNA during physical exercise occurs independent of extracellular vesicles.Eur J Appl Physiol. 2015 Jul 1.
  • Tug S, Helmig S, Deichmann ER, Schmeier-Jürchott A, Wagner E, Zimmermann T, Radsak M, Giacca M, Simon P. Exercise-induced increases in cell free DNA in human plasma originate predominantly from cells of the haematopoietic lineage. Exerc Immunol Rev. 2015;21:164-173.
  • Dettweiler U, Unlu A, Lauterbach G, Legl A, Simon P, Kugelmann C. Alien at home: Adjustment strategies of students returning from a six-months over-sea's educational programme. International Journal of Intercultural Relations, Jan 2015; Volume: 44, Pages: 72-87.


  • Moser DA, Braga L, Raso A, Zacchigna S, Giacca M, Simon P. Transgene Detection by Digital Droplet PCR. PLoS One. 2014 Nov 6;9(11):e111781. eCollection 2014.
  • Tug S, Helmig S, Menke J, Zahn D, Kubiak T, Schwarting A, Simon P.Correlation between cell free DNA levels and medical evaluation of disease progression in systemic lupus erythematosus patients. Cell Immunol. 2014 Aug 20;292(1-2):32-39.
  • Hoffmann SW, Tug S, Simon P. Child-caregivers' body weight and habitual physical activity status is associated with overweight in kindergartners. BMC Public Health. 2014 Aug 9;14:822
  • Breitbach S, Tug S, Simon P. Conventional and Genetic Talent Identification in Sports: Will Recent Developments Trace Talent? Sports Med. 2014 Jul 12.
  • Dietz P, Ulrich R, Niess A, Best R, Simon P, Striegel H. Prediction Profiles for Nutritional Supplement Use Among Young German Elite Athletes. Int J Sport Nutr Exerc Metab. 2014 Jun 5.
  • Breitbach S, Sterzing B, Magallanes C, Tug S, Simon P.Direct measurement of cell-free DNA from serially collected capillary plasma during incremental exercise. J Appl Physiol (1985). 2014 Jul 15;117(2):119-30.
  • Breitbach S, Tug S, Helmig S, Zahn D, Kubiak T, Michal M, Gori T, Ehlert T, Beiter T, Simon P. Direct quantification of cell-free, circulating DNA from unpurified Plasma. PLoS One. 2014 Mar 3;9(3):e87838. eCollection 2014


  • Goeppert B, Schmidt CR, Geiselhart L, Dutruel C, Capper D, Renner M, Vogel MN, Zachskorn C, Zinke J, Campos B, Schmezer P, Popanda O, Wick W, Weller M, Meyermann R, Schittenhelm J, Harter PN, Simon P, Weichert W, Schirmacher P, Plass C, Mittelbronn M. Differential Expression of the Tumor Suppressor A-Kinase Anchor Protein 12 in Human Diffuse and Pilocytic Astrocytomas Is Regulated by Promoter Methylation. J Neuropathol Exp Neurol. 2013 Oct;72(10):933-941.
  • Hoffmann SW, Tug S, Simon P. Obesity prevalence and unfavorable health risk behaviors among German kindergarten teachers: cross-sectional results of the kindergarten teacher health study. BMC Public Health. 2013 Oct 4;13(1):927.
  • Michal M, Simon P, Gori T, König J, Wild PS, Wiltink J, Tug S, Sterzing B, Unterrainer J, Münzel T, Beutel ME. Psychodynamic Motivation and Training program (PMT) for the secondary prevention in patients with stable coronary heart disease: study protocol for a randomized controlled trial of feasibility and effects. Trials. 2013 Sep 25;14(1):314. [Epub ahead of print]
  • Franke AG, Bagusat C, Dietz P, Hoffmann I, Simon P, Ulrich R, Lieb K. Use of illicit and prescription drugs for cognitive or mood enhancement among surgeons. BMC Med. 2013 Apr 9;11:102.
  • Ehlert T, Simon P, Moser DA. Epigenetics in sports.Sports Med. 2013 Feb;43(2):93-110.
  • Dietz P, Striegel H, Franke AG, Lieb K, Simon P, Ulrich R. Randomized response estimates for the 12-month prevalence of cognitive-enhancing drug use in university students. Pharmacotherapy. 2013 Jan;33(1):44-50.


  • Ernst S, Simon P. A quantitative approach for assessing significant improvements in elite sprint performance: Has IGF-1 entered the arena? Drug Test Anal. 2012 Aug 29.
  • Ulrich R, Schröter H, Striegel H, Simon P. Asking Sensitive Questions: A Statistical Power Analysis of Randomized Response Models. Psychol Methods. 2012 Aug 27.
  • Springer F, Ehehalt S, Sommer J, Ballweg V, Machann J, Binder G, Claussen CD, Schick F, DISKUS-Study Group. Predicting volumes of metabolically important whole-body adipose tissue compartments in overweight and obese adolescents by different MRI approaches and anthropometry. Eur J Radiol. 2012 Jul;81(7):1488-94.
  • Hoffmann S, Ulrich R, Simon P. Refined analysis of the critical age ranges of childhood overweight - implications for primary prevention. Obesity (Silver Spring). 2012 Jun 20.
  • Breitbach S, Tug S, Simon P. Circulating cell-free DNA: An up-coming molecular marker in exercise physiology, Sports Med. 2012 Jul 1;42(7):565-86.
  • Dietz P, Hoffmann S, Lachtermann E, Simon P. The influence of exclusive resistance training on body composition and cardiovascular risk factors in overweight or obese children: a systematic review, Obesity Facts 2012 Jul 27;5(4):546-560.
  • Moser DA, Neuberger EW, Simon P. A quick one-tube nested PCR-protocol for EPO transgene detection. Drug Test Anal. 2012 Apr 26.
  • Neuberger EW, Jurkiewicz M, Moser DA, Simon P. Detection of EPO gene doping in blood. Drug Test Anal. 2012 Apr 17.
  • Schum J, Blumenstock G, Weber K, Schweizer R, Pfaff C, Schurr N, Ranke MB, Binder G, Ehehalt S, DISKUS-Study Group. Variants of the FTO Gene in Obese Children and their Impact on Body Composition and Metabolism before and after Lifestyle Intervention. Exp Clin Endocrinol Diabetes. 2012 Mar;120(3):128-31.
  • Kuschel A, Simon P, Tug S Functional regulation of HIF-1alpha under normoxia - is there more than post-translational regulation? Journal of cellular physiology. 2012 Feb;227(2):514-24.
  • Breitbach S, Beiter T, Hudemann J, Striegel H, Simon P. Circulating, cell-free DNA concentrations in human plasma of soccer players before and after a typical soccer training session. Acta Physiologica, 2012.


  • Breitbach S, Bohringer A, Simon P, Tug S. The differential expression of several mRNA variants of HIF1a during endurance exercise and under normobar hypoxia. Acta Physiologica 2011; Volume 201, Supplement 682 The 90th Annual Meeting of The German Physiological Society 26/03/2011-29/03/2011 Regensburg, Germany
  • Neuberger EW, Moser DA, Simon P. Principle considerations for the use of transcriptomics in doping research. Drug Test Anal. 2011 Oct;3(10):668-75.
  • Ehehalt S, Binder G, Schurr N, Pfaff C, Ranke MB, Schweizer R; DISKUS-Study Group. The functional muscle-bone unit in obese children - altered bone structure leads to normal strength strain index. Exp Clin Endocrinol Diabetes. 2011 Jun;119(6):321-6.
  • Springer F, Ehehalt S, Sommer J, Ballweg V, Machann J, Binder G, Claussen CD, Schick F; DISKUS-Study Group. Assessment of relevant hepatic steatosis in obeseadolescents by rapid fat-selective GRE imaging with spatial-spectral excitation: a quantitative comparison with spectroscopic findings. Eur Radiol. 2011 Apr;21(4):816-22.
  • Beiter T, Fragasso A, Hudemann J, Nieß AM, Simon P. Short-Term Treadmill Running as a Model for Studying Cell-Free DNA Kinetics In Vivo. Clin Chem. 2011 Apr;57(4):633-636.
  • Beiter T, Zimmermann M, Fragasso A, Hudemann J, Niess AM, Bitzer M, Lauer UM, Simon P. Direct and long-term detection of gene doping in conventional blood samples. Gene Ther. 2011 Mar;18(3):225-31.
  • Nolte A, Secker S, Walker T, Greiner TO, Neumann B, Simon P, Ziemer G, Wendel HP. Veins are no arteries: even moderate arterial pressure induces significant adhesion molecule expression of vein grafts in an ex vivo circulation model. J Cardiovasc Surg (Torino). 2011 Apr;52(2):251-9.
  • Walsh NP, Gleeson M, Shephard RJ, Gleeson M, Woods JA, Bishop NC, Fleshner M, Green C, Pedersen BK, Hoffman-Goetz L, Rogers CJ, Northoff H, Abbasi A, Simon P. Position statement. Part one: Immune function and exercise. Exerc Immunol Rev. 2011;17:6-63. Review.
  • Schittenhelm J, Simon P, Harter PN, Zachskorn C, Schlaszus H, Röttger F,Winkels M, Weller M, Meyermann R, Mittelbronn M. CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms. Histopathology. 2011 Apr;58(5):739-49.
  • Ehehalt S, Schweizer R, Blumenstock G, Pfaff C, Schurr N, Weber K, Ranke MB, Binder G; DISKUS-Study Group. Investigation of myostatin serum levels before and after a 6-month lifestyle intervention program in obese children. Exp Clin Endocrinol Diabetes. 2011 Apr;119(4):238-42.
  • Springer F, Ehehalt S, Sommer J, Ballweg V, Machann J, Binder G, Claussen CD, Schick F; for the DISKUS-Study Group. Assessment of relevant hepatic steatosis in obese adolescents by rapid fat-selective GRE imaging with spatial-spectral excitation: a quantitative comparison with spectroscopic findings. Eur Radiol. 2011 Apr;21(4):816-22.
  • Ehehalt S, Schweizer R, Blumenstock G, Pfaff C, Schurr N, Weber K, Ranke MB, Binder G; for the Diskus Study Group. Investigation of myostatin serum levels before and after a 6-month lifestyle intervention program in obese children. Exp Clin Endocrinol Diabetes. 2011 Apr;119(4):238-42.
  • Beiter T, Fragasso A, Hudemann J, Niess AM, Simon P. Taking Advantage of Exercise: Short-Term Treadmill Running as a Model for Studying Cell-Free DNA Kinetics in vivo. Clin Chem. 2011 Apr;57(4):633-6.
  • Ehlert T, Simon P Genetik und Epigenetik der körperlichen Leistungsfähigkeit  
  • Beiter T, Zimmermann M, Fragasso A, Hudemann J, Niess AM, Bitzer M, Lauer UM, Simon P.  Direct and long-term detection of gene doping in conventional blood samples.Gene Ther. 2011 Mar;18(3):225-31 


  • Striegel H, Ulrich R, Simon P. Randomized response estimates for doping and illicit drug use in elite athletes. Drug Alcohol Depend. 106(2-3):230-2.
  • Ciobanu DC, Lu L, Mozhui K, Wang X, Jagalur M, Morris JA, Taylor WL, Dietz K, Simon P, Williams RW. Detection, validation, and downstream analysis of allelic variation in gene expression. Genetics, 184(1):119-28.
  • Springer F, Nguyen HP, Machann J, Schweizer R, Ranke MB, Binder G, Schick F, Ehehalt S, Neu A, Haber HP, Schurr N, Pfaff C, Simon P, Lacroix A, Niess A, Giel K, Schrauth M, Enck P, Zipfel S, Urschitz MS. Normal-weight 14-year-old girl with acanthosis nigricans and markedly increased hepatic steatosis: evidence for the important role of ectopic fat deposition in the pathogenesis of insulin resistance in childhood and adolescence. Horm Res Paediatr. 74(5):376-80.
  • Lehmann R, Zhao X, Weigert C, Simon P, Fehrenbach E, Fritsche J, Machann J, Schick F, Wang J, Hoene M, Schleicher ED, Häring HU, Xu G, Niess AM. Medium chain acylcarnitines dominate the metabolite pattern in humans under moderate intensity exercise and support lipid oxidation. PLoS One. 5(7):e11519.
  • Ehlert T, Simon P, Tug S. Misleading interpretations and public misinformation on human growth hormone in athletes. Ann Intern Med. 153(5):345-6.


  • Hansel J, Solleder I, Gfroerer W, Muth CM, Paulat K, Simon P, Heitkamp HC, Niess A, Tetzlaff K. Hypoxia and cardiac arrhythmias in breath-hold divers during voluntary immersed breath-holds. Eur J Appl Physiol. 2009 Mar;105(5):673-8.
  • Schittenhelm J, Beschorner R, Simon P, Tabatabai G, Herrmann C, Schlaszus H, Capper D, Weller M, Meyermann R, Mittelbronn M. Diagnostic value of WT1 in neuroepithelial tumours. Neuropathol Appl Neurobiol. 2009 Feb;35(1):69-81.
  • Mittelbronn M, Harter P, Warth A, Lupescu A, Schilbach K, Vollmann H, Capper D, Goeppert B, Frei K, Bertalanffy H, Weller M, Meyermann R, Lang F, Simon P. Egr-1 is regulated by NMDA receptor stimulation and associated with patient survival in human high grade astrocytomas.Brain Pathol. 2009 Apr;19(2):195-204. 
  • Küster O, Simon P, Mittelbronn M, Tabatabai G, Strik H, Dietz K, Roser F, Meyermann R, Schittenhelm J. Erythropoietin receptor is expressed in meningiomas and lower levels are associated with tumor recurrence. Neuropathol. Appl. Neurobiol., 35(6):555-65.
  • Hansel J, Simon P. Re: Body mass index and vigorous physical activity and the risk of heart failure among men. Circulation, 120(11):e90.
  • Striegel H, Simon P, Hansel J, Best R, Niess A. Reproducibility of Determining Anaerobic Capacity Using Treadmill Ergometry. The Open Sports Medicine Journal, 3, 55-58.
  • Schaible E, Boehringer A, Callau D, Nieß AM, Simon P. Exercise and menstrual cycle dependent expression of a truncated alternative splice variant of HIF1α in leukocytes. Exercise Immunol review, 15:145-56.
  • Avci-Adali M, Nolte A, Simon P, Ziemer G, Wendel HP. Porcine EPCs downregulate stem cell markers and upregulate endothelial maturation markers during in vitro cultivation. J Tissue Eng Regen Med, 3(7):512-20.
  • Nolte A, Raabe C, Walker T, Simon P, Ziemer G, Wendel HP. Optimized basic conditions are essential for successful siRNA transfection into primary endothelial cells. Oligonucleotides, 19(2):141-50.


  • Merseburger AS, Hennenlotter J, Kuehs U, Simon P, Kruck S, Koch E, Stenzl A, Kuczyk MA.  Activation of PI3K Is Associated with Reduced Survival in Renal Cell Carcinoma. Urologia Internationalis, 80:372-377.
  • Nieß AM, Striegel H, Hipp A, Hansel J, Simon P.Antioxidant supplementation in sports – sense or non-sense? Deutsche Zeitschrift für Sportmedizin, 59: 55-61.
  • Hennenlotter J, Ohneseit PA, Simon P, Merseburger AS, Serth J, Kuehs U, Kramer M, Hartmann JT, Stenzl A, Kuczyk MA. PTEN and p27Kip1 are not downregulated in the majority of renal cell carcinomas -implications for Akt activation. Oncol Rep. 19: 1141-1147.
  • Merseburger AS, Kramer MW, Hennenlotter J, Simon P, Knapp J, Hartmann JT, Stenzl A, Serth J, Kuczyk MA. Involvement of decreased Galectin-3 expression in the pathogenesis and progression of prostate cancer. Prostate, 68: 72-77.
  • Schwab M, Lupescu A, Mota M, Mota E, Frey A, Simon P, Mertens PR, Floege J, Luft F, Asante-Poku S, Schaeffeler E, Lang F. Association of SGK1 Gene Polymorphisms with Type 2 Diabetes. Cell. Physiol. Biochem., 21:151-60.
  • Hansel J, Simon P. Still without impact on adverse postoperative outcomes: Preoperative statin therapy in patients undergoing cardiac surgery. Eur. Heart J., in press.
  • Beiter T, Zimmermann M, Fragasso A, Armeanu S, Lauer UM, Bitzer M, Su H, Young WL, Niess AM, Simon P. Establishing a novel single-copy primer-internal intron-spanning PCR (spiPCR) procedure for the direct detection of gene doping. Exercise Immunol. review, 14:73-85.
  • Northoff H, Symons S, Zieker D, Schaible EV, Schäfer K, Thoma S, Löffler M, Abbasi A, Simon P, Niess AM, Fehrenbach E. Gender- and menstrual phase dependent regulation of inflammatory gene expression in response to aerobic exercise. Exercise Immunol. review, 14:86-103.


  • Beschorner R*, Dietz K, Schauer N, Mittelbronn M, Schluesener HJ, Trautmann K, Meyermann R, Simon P. (2007) Expression of EAAT1 reflects a possible neuroprotective function of reactive astrocytes and activated microglia following human traumatic brain injury. Histology and Histopathology, 22: 515-526.
  • Warth A, Simon P, Capper D, Goeppert B, Ajaaj R, Tabatabai G, Stubenvoll F, Merseburger AS, Weller M, Meyermann R, Wolburg H, Mittelbronn M. (2007) Expression pattern of the water channel aquaporin-4 in human gliomas is associated with blood-brain barrier disturbance but not with patient survival. J Neurosci Res, 85: 1336-46.
  • Mittelbronn M, Capper D, Bunz B, Dietz K, Goeppert B, Ajaaj R, Tabatabai G, Stubenvoll F, Schlaszus H, Merseburger AS, Becker R, Freudenstein D, Wick W, Weller M, Meyermann R, Simon P. (2007) De novo erythropoietin receptor (EPO-R) expression in human neoplastic glial cells decreases with grade of malignancy but positively influences patients’ survival in high grade gliomas. Neuropathol. Appl. Neurobiol. 33: 299-307.
  • Beschorner R*, Simon P*, Schauer N, Mittelbronn M, Schluesener HJ, Trautmann K, Dietz K, Meyermann R. (2007) EAAT1 but not EAAT2 is expressed by reactive astrocytes and activated microglial cells following human cerebral ischemia. Histopatology 50: 897-910. *Both Authors contributed equally
  • Vollmann H, Wölfel S, Ohneseit P, Stransky E, Vonthein R, Wick W, Meyermann R, Simon P. (2007) Differential expression of Egr1 and activation of microglia following irradiation in the rat brain. Strahlenther Onkol, 183: 248-255.
  • Hansel J, Simon P. (2007) Sekundärprävention der koronaren Herzerkrankung durch Bewegung - Was ist gesichert? Deutsche Zeitschrift für Sportmedizin, 58: 65-66.
  • Walker T, Wendel HP, Tetzloff L, Raabe C, Heidenreich O, Simon P, Scheule AM, Ziemer G. (2007) Inhibition of adhesion molecule expression on human venous endothelial cells by non-viral siRNA transfection. J Cell Mol Med., 11: 139-47.
  • Niess AM, Simon P. (2007) Response and adaptation of skeletal muscle to exercise – the role of reactive oxygen species. Front. Biosci., 12: 4826-38.
  • Mehling M, Simon P, Mittelbronn M, Meyermann R, Ferrone S, Weller M, Windel H. (2007) WHO grade associated downregulation of MHC class I antigen-processing machinery components in human astrocytomas: does it reflect a potential immune escape mechanism? Acta Neuropathol., 114: 111-119.
  • Beiter T, Reich E, Weigert C, Niess AM, Simon P. (2007) Sense or antisense? False-priming reverse transcription controls are required for determining sequence orientation by RT-PCR. Anal Biochem., 369: 258-61.
  • Schilbach K, Schick J, Wehrmann M, Wollny G, Simon P, Schlegel PG, Eyrich M. (2007) PD-1–PD-L1 pathway is involved in suppressing alloreactivity of heart infiltrating T cells during murine GvHD across minor histocompatibility antigen barriers. Transplantation, 84: 214-222.
  • Mittelbronn M*, Simon P*, Löffler C, Capper D, Bunz B, Harter P, Schlaszus H, Schleich A, Tabatabai G, Goeppert B, Meyermann R, Weller M, Wischhusen J. (2007) Elevated HLA-E levels in human glioblastomas but not in grade I to III astrocytomas correlate with infiltrating CD8+ cells. J. Neuroimmunol., 189: 50-58. *Both Authors contributed equally
  • Weigert C, Düfer M, Simon P, Runge H, Brodbeck K, Häring HU, Schleicher ED. (2007) Regulation of IL-6 expression by AMPK and IL-6 in skeletal muscle cells. Am J. Physiol. - Cell Ph, 293: C1139-1147.
  • Weyrich P, Machicao F, Staiger H, Simon P, Thamer C, Machann J, Schick F, Guirguis A, Fritsche A, Stefan N, Häring HU.(2007) Role of AMP-activated protein kinase 3 genetic variability in glucose and lipid metabolism in non-diabetic Caucasians. Diabetologia, 50: 2097 - 2106.
  • Simon P, Schneck M, Hochstetter T, Koutsouki E, Mittelbronn M, Merseburger AS, Weigert C, Niess AM, Lang F. (2007) Differential regulation of serum- and glucocorticoid-induced kinase 1 (SGK1) splice variants based on alternative initiation of transcription. Cell. Physiol. Biochem., 20:715-728.


  • Striegel H*, Simon P*, Frisch S, Roecker K, Dietz K, Dickhuth HH, Ulrich R. (2006) Anabolic Ergogenic Substance Users in Fitness-Sports: A Distinct Group Supported by the Health Care System. Drug and Alcohol Dependence, 81: 11-19.
    *Both Authors contributed equally
  • Striegel H, Simon P, Wurster C, Ulrich R, Niess AM. (2006) The Use of Nutritional Supplements among Master Athletes. Int. J. Sports Medicine, 27: 236-241.
  • Merseburger AS, Hennenlotter J, Simon P, Mueller CC, Kuehns U, Knuechel-Clarke R, Moul JW, Stenzl A, Kuczyk MA.(2006) Activation of the PKB/Akt pathway in histological benign prostatic tissue adjacent to the primary malignant lesions Oncol Rep, 1:79-83.
  • Simon P*, Striegel H*, Aust F, Dietz K, Ulrich R. (2006) Doping in fitness sports: estimated number of unreported cases and individual probability of doping. Addiction, 101:1640-4.
    *Both Authors contributed equally
  • Mittelbronn M, Dietz K, Simon P, Beschorner R, Schleich A, Nguyen TD, Meyermann R, Schlaszus H. (2006) Albumin in Immunohistochemistry: Foe and Friend. Appl Immunohistochem Mol Morphol, 14:441-444.


  • Striegel H, Rössner D, Simon P, Niess AM. (2005) The World Anti-Doping Code 2003 - Consequences for Physicians Associated with Elite Athletes. Int. J. Sports Medicine, 3: 238-43
  • Richartz E, Batra A, Simon P, Wormstall H, Bartels M, Buchkremer G, Schott K. (2005) Diminished Production of Proinflammatory Cytokines in Patients with Alzheimer's Disease. Dement Geriatr Cogn Disord,. 19:184-188
  • Striegel H, Simon P, Furian T, Nieß A. (2005) Liste der verbotenen Substanzen 2005 – Konsequenzen für die Behandlung von Leistungssportlern. Sportorthopädie Sporttraumatologie, 21: 117-120
  • Richartz E, Stransky E, Batra A, Simon P, Lewczuk P, Buchkremer G, Bartels M, Schott K. (2005) Decline of immune responsiveness: A pathogenetic factor in Alzheimer's disease? J Psychiatr Res. 39:535-43.
  • Neumann M, Mittelbronn M, Simon P, B. Van Massenhove, R. de Silva, Lees A, Meyermann R, Kretzschmar HA. (2005) Novel Family with Frontotemporal Dementia showing Intronic 10 + 3 Splice Site Mutation in the Tau Gene: Neuropathology and Molecular Effects. Neuropathology Appl. Neurobiology, 31:362-73.
  • Merseburger A, Hennenlotter J, Simon P, Ohneseit PA, Kuehs U, Kruck S, Koch E, Vogel U, Stenzl A, Kuczyk MA. (2005) Cathepsin D Expression in renal cell cancer – biological and clinical implications. European Urology, 48:519-26.
  • Hoffmann J*, Simon P*, Zimmermann AK, Lemancyk M, Walter T, Beyer M, Hoffmeister HM, Ziemer G, Wendel HP. (2005) Thrombospondin 1 as possible key factor in the hemocompatibility of endocoronary prostheses. Biomaterials, 26: 5240-50
    * Both Authors contributed equally
  • Merseburger A, Hennenlotter J, Simon P, Kruck S, Koch E, Horstmann M, Kuehs U, Küfer R, Vogel U, Stenzl A, Kuczyk MA. (2005) Membranous Expression and Prognostic Implications of Epidermal Growth Factor Receptor Protein in Human Renal Cell Cancer. Anticancer Research, 25: 1901-1907.
  • Zieker D, Fehrenbach E, Dietzsch J, Fliegner J, Weidmann M, Nieselt K, Gebicke-Haerter P, Spanagel R, Simon P, Niess AM, Northoff H. (2005) cDNA-microarray analysis reveals novel candidate genes expressed in human peripheral blood following exhaustive exercise. Physiol. Genomics, 23: 287-94.


  • Buck C, Schaeffel F, Simon P, Feldkaemper M. (2004) Effects of Plus and Minus Lens Treatment on Retinal and Choroidal Glucagon and Glucagon Receptor mRNA Levels in the Chicken. Invest Ophthalmol Vis Sci. 45: 402–409.
  • Simon P, Feldkaemper M, Ohngemach S, Bitzer M, Schaeffel F. (2004) Early transcriptional changes of retinal and choroidal TGF β-2, RALDH-2, and ZENK following imposed positive and negative defocus in chickens. Mol.Vision 10: 588-97.
  • Simon P, Schott K, Williams RW, Schaeffel F. (2004) Post-transcriptional regulation of the immediate early gene EGR1 by light in the mouse retina. Europ. J. of Neurosci 20: 3371-7.
  • Ohngemach S, Buck C, Simon P, Schaeffel F, Feldkaemper M. (2004) Temporal changes of novel transcripts in the chicken retina following imposed defocus. Mol.Vision, 10: 1019-24.
  • Richartz E, Klein R, Stransky E, Simon P, Batra A, Laske C, Bartels M, Buchkremer G, Schott K. (2004) Autoantibody Reactivity in Serum and Cerebrospinal Fluid of Patients with Alzheimer’s Disease. NPBR, 11: 145-48.
  • Schwab JM, Schluessener HJ, Simon P. (2004) Novel neuroscience M.D.-Ph.D. programs in Germany: a chance for neurosurgical research? Neurosurgery, 55:1232-3.


  • Simon P. (2003) Q-Gene: Processing Quantitative Real-Time RT-PCR Data. Bioinformatics 19(11): 1439-40.
  • Zimmermann AK, Simon P, Seeburger J, Hoffmann J, Ziemer G, Aebert H, Wendel HP. (2003) Cytokine gene expression in monocytes of patients undergoing cardiopulmonary bypass surgery evaluated by real-time PCR. J Cell Mol Med. 7(2): 146-56.


  • Dettweiler U, Simon P. (2001) Points to consider for Ethics Committees in Human Gene Therapy Trials. Bioethics 5(6): 491-500.


  • Simon P, Vorwerk CK, Mansukani S, Chen SJ, Wilson JM, Zurakowski D, Bennett J, Dreyer EB. Bcl-2 gene therapy exacerbates excitotoxicity. Human Gene Therapy, 1999;10:1715-1720.
  • Vorwerk CK, Simon P, Gorla M, Katowitz W, Zurakowski D, Levin LA, Dreyer EB. Pilocarpine is toxic to retinal ganglion cells. Invest Ophthalmol Vis Sci, 1999;40:813-816.
  • Simon P, McConnell DJ, Zurakowski D, Vorwerk CK, Naskar R, Grosskreutz CL, Dreyer EB. Thy-1 is critical for normal retinal development. Brain Res Dev Brain Res, 1999;117: 219-223.
  • Dreyer EB, Vorwerk CK, Zurakowski D, Simon P, Bennett J. Infection with adeno-associated virus may protect against excitoxicity. Neuroreport, 1999;10: 2887-2890.


  • Simon P, Thanos S. Combined methods of retrograde staining, layer separation and viscoelastic cell stabilization to isolate retinal ganglion cells in adult rats. J. Neurosci. Methods, 1998;83:113-124.


  • Beiter T, Reich E, Williams RW, Simon P. (2008) Antisense transcription: A critical look in both directions. Cell Mol Life Sci. 2009 Jan;66(1):94-112.
  • Striegel H, Simon P. (2007) Doping : High-tech cheating in sport. Internist, 48:737-742. 59.
  • Simon P, Fehrenbach E, Nieß AM. (2006) Regulation of immediate early gene expression by exercise: Short cuts for the adaptation of immune function. Exercise Immunol. review, 12:112-31.
  • Merseburger AS, Anastasiadis AG, Hennenlotter J, Koch EC, Kruck S, Simon P, Machtens SA, Serth J, Moul JW, Stenzl A, Kuczyk MA. (2006) Tissue Microarrays: Applications in Urological Cancer Research. World J. Urology, 24: 579-84.
  • Schaeffel F, Simon P, Feldkaemper M, Ohngemach S, Williams RW. (2003) Molecular biology of myopia. Clin Exp Optom. 86: 295-307.


Applications for Patents 

  • Simon P. (2006) „Nachweis von transgener DNA (tDNA)“, Schutzrecht DE 10 2006 021 257.6
  • Simon P. (2007) „Detection of transgenic DNA (tDNA)“, PCT/EP2007/003385



  • Simon P. (2000) Eine Methodik der retrograden Zellmarkierung, Zellschichtseparierung und viskoelastischer Zellstabilisierung zur Anreicherung adulter retinaler Ganglienzellen der Ratte. Medizinische Fakultät der Universität Tübingen; Promotion zum „Dr. med“.
  • Simon P. (2004) Genexpressionsprofile während der Entwicklung visuell induzierter Refraktionsfehler und deren pharmakologische Beeinflussung. 2004, Graduate School of Neural and Behavioral Sciences / International Max Planck Research School: Tübingen; Promotion zum „Dr. rer.nat.“